Get 2% OFF at the First BUY (Selected Pills) - Shop Now!

Soma 350mg Vs Soma 500mg- Are they the same?

Soma 350mg Vs Soma 500mg- Are they the same?

Body pain can be very challenging for most of us. I am sure you are very well aware of the pain that runs down the spine when we twist or turn our backs the wrong way. Or the agonizing sensation from long hours of desk work. It is during this time that Soma medication comes into play. It is a muscle relaxer that blocks pain stimulation from reaching the person's brain. Soma 350mg Vs. Soma 500mg is one of the most discussed topics of this muscle relaxer. Since they belong to the same class of drugs, it is hard for most people to decide. This extensive study of the most potent Carisoprodol dose helps users buy the Soma pill correctly. 


What Are The Similarities Between Soma 500mg And Soma 350mg?

This muscle relaxer is a prescription drug for treating acute pain in people. It is the brand name of Carisoprodol and is available in several different trade or brand names. Soma medication comes in two dosages, i.e., Soma 350mg and Soma 500mg. Since they have the same active compound, they show several similarities in their action and usage. 


Table 1: Soma 350mg Vs Soma 500mg- Similarities 


Soma 350mg

Soma 500mg

Active compound 



Prescription usage 

Joints and Muscle pain

Discomfort in the muscle and joints 

Brand names 

Pain o Soma 350mg, Watson Soma 350mg, Prosoma 350mg, 2410 V pill

Watson Soma 500mg, Pain o Soma 500mg, Prosoma 500 mg

Pregnancy Category 

Category C

Category C

Drug class [1]



Drug Category 

Muscle relaxer 

Muscle relaxer 

FDA approved 



Mechanism of action

Affecting the CNS of the body

Targeting the CNS of the body 

Onset of action

30 minutes

30 minutes

Soma's legal Status [1]

USA- Schedule IV


Canada- Schedule I, sub-schedule F1


Australia- Not available over the counter. One can get Soma 350mg online without any restrictions. 

Canada- Schedule I, sub-schedule F1


USA-Schedule IV


Australia- prescription medicine, but one can get Soma 500mg online. 


Thus, to answer the most potent strength of Soma medication, we can say that both doses will show almost the same effects on the user. 

How Does Soma 350mg And Soma 500mg Differ?

The battle of Soma 350mg Vs. Soma 500mg has been long, and we wish to find answers to all the questions in this article. One such common question is, “What is the strongest mg of Soma?” The answer depends on the action and efficacy of both the medication doses. These Soma medication doses follow the same mode of action but differ in effectiveness. 


Table 2: Soma 500mg Vs Soma 500mg- differences 


Soma 350mg

Soma 500mg

Active compound 

Carisoprodol 350 mg

Carisoprodol 500mg 

Frequency to cause side effects 




Slightly lower in comparison to Soma 500mg 


Withdrawal symptoms 

Less severe 

More severe 

Prone to dependency 




Soma 350mg Vs. Soma 500mg- Dosage Information

Both medication doses follow a similar mode of administration. The correct intake of Soma medication is essential to avoid side effects. Improper dosing of the pill is a common cause of addiction and dependency in the user. 


Table 3: Direction to taking the Soma pill 


Soma 350mg

Soma 500mg

Route of intake 



Long-term use of Carisoprodol 

Do not take it for more than three weeks 

Discontinue the intake of Soma 500mg after three weeks 

Efficacy of the drug

The action of the Soma 350mg muscle relaxer lasts for 4 to 5 hours 

Soma 500mg effects last for about 6 hours in the user

Dosing Gap

Retake the medicine after about 4 hours 

Take another dose after 5 to 6 hours interval of the previous dose

Recommended dose

3 to 4 times

Maximum of 2 to 3 times 

Food indication

Light meal before or after dosing

The intake of a light meal is advisable 

For beginners 

More advisable 

Less advisable 


The use of Soma 350mg is advisable for beginners. If users do not get complete relief from pain with a lower dose, such people can take Soma 500mg. However, it is essential to note that using higher doses of Soma medication is advisable under the guidance of a doctor. 

Carisoprodol Precaution And Warning

Using both the dosages of Soma 350mg vs. Soma 500mg is safe, with a few reports of side effects. However, under certain conditions, the intake of the muscle relaxer is not advisable. Users taking the medication under the guidance of a physician should follow the instructions given by their health professional. However, people taking these muscle relaxers without a valid prescription must avoid the drug in the following cases. 


Table 4: Carisoprodol warnings 


Soma pill usage indication 

Health disorder 

People with hepatic, renal, and cardiac disorders are recommended to take Soma pain medication after consulting a physician.

Pregnancy and lactating women

The use of Soma pills in pregnancy and lactating women is not advisable. Carisoprodol is a category C medication and should be taken with a valid medical prescription. 

Elderly people 

The prescription use of Soma 350mg and Soma 500mg is not for people above the age of 65 years. 


People under the age of 17 years should take Soma pills after talking to a doctor. 

History of abuse 

Users with a previous history of substance abuse can take Soma pills after consulting a doctor. 


Carisoprodol Drug Interaction

Using other medications with this pain medication can cause drug interaction in the user. One should avoid such interactions as they can drastically lower the potency of the muscle relaxer. Both Soma 350mg vs. Soma 500mg interact with other treatments and medication to cause side effects. 


Table 5: List of medications for possible soma drug interaction 


Carisoprodol dosage 




Both the Soma dosage 

Dizziness and Drowsiness 

Mixing Carisoprodol and alcohol does not require immediate medical attention 

Apalutamide [2]

Both the Soma dosage 

It affects the hepatic enzyme of the body, thus further decreasing the concentration of Carisoprodol in the body. 

The interaction of the Soma pill with apalutamide needs medical attention. 

Baclofen [2]

Both the Soma dosage 

Increase sedation 

Immediate medical help is not required 

Codeine [2]

Both the Soma dosage 

Increase sedation 

Immediate medical help is not required 

Hydrocodone [2]

Both the Soma dosage 

Increase the toxicity of the other drug

It can cause severe issues for the user. 

Cenobamate [2]

Both the Soma dosage 

The level of Carisoprodol in the body increases

In a severe condition, call a doctor immediately. 

Cyclobenzaprine [2]

Both the Soma dosage 

Increase the level of sedation 

Do not require medical help 


Table 5 does not list all the possible medical interactions of the pain medication. People should avoid taking other tablets with Carisoprodol, also known as 2410 V pills. There are also several questions regarding the intake of the pills with other medications.

Here are answers to some commonly asked questions on muscle relaxer drug interaction.


Can Carisoprodol be taken with Ibuprofen?

Ibuprofen is the standard first line of treatment for managing acute pain in people. It belongs to the drug class of Nonsteroidal anti-inflammatory medication. The pain medication dosages Soma 350mg vs. Soma 500mg with Ibuprofen do not report any drug interactions between the two medications [3]. However, it is essential to consult a physician before taking the pill with Ibuprofen. 


Is it safe to take Tylenol with Carisoprodol?

Tylenol helps in relieving mild to moderate pain in the body. Tylenol is handled with a muscle relaxer and does not cause severe side effects. But, it is essential to note that this interaction may differ between people. 


Can you take Aspirin and Carisoprodol together?

The muscle relaxer pills already have Aspirin in their formulation. One tablet of Carisoprodol contains approximately 325mg of Aspirin. Thus, it is best to avoid the intake of Aspirin with the muscle relaxer. 


Is it safe to take Carisoprodol with Tramadol?

Both medications are prescription medications. Taking both pills together can exponentially increase the chances of experiencing side effects and dependency on the user. 

Another commonly asked question on the interaction of the Soma pill is, "Can you take gabapentin and muscle relaxers together?" These interactions are most common in people struggling with severe body pain and combine the two analgesics for a better result. However, such interactions can cause breathing problems, depression, and allergic reactions in users. 


Soma 350mg Vs. Soma 500mg- Which Is More Affordable?


Soma 350mg Vs Soma 500mg


The price of the medication differs depending on the strength of the muscle relaxer. The cost of the 350mg pill is comparatively less than that of the 500mg pill. It also depends on the package of the medication that you choose to purchase. The price of the 350mg dose at Healthnaturo is $1.34. The cost of the 500mg dose is also $1.34 for 400 pills. However, this price differs from one site to another. People looking for an affordable choice of Soma medication are advised to choose the 350mg dose.

Soma 350mg Vs. Soma 500mg- Which Is More Prone To Abuse?

The 500mg dose of the pain medication is more prone to abuse and addiction. It is a higher dosage that has a higher tendency for dependency. It also is more prone to cause withdrawal symptoms in the user. A study report by Mackram F. MD et al. [4] showed signs of anxiety, psychosis, and ataxia after abruptly discontinuing the Carisoprodol dosage. While stopping using the muscle relaxer, it is essential first to lower the dose of the medication. Then, gradually terminate the intake entirely.

What is the most potent mg of Soma- Our final thought on the muscle relaxer?

The use of this pain medication is advisable for all people who have acute skeletomuscular discomfort. To answer "what is the strongest mg of Soma," it is essential to note the differences in the Soma medication dosages. These differences can affect their action and efficacy. Both the medication doses, Soma 350mg vs. Soma 500mg, show a similar mode of action with Carisoprodol as their active compound. Considering the efficacy, we can conclude that the 500mg dose is the most potent mg of the muscle relaxer. People who have not taken this muscle relaxer should start with 350mg. Higher doses of the medication, such as 500mg, must be taken after consulting a doctor. The price of 350mg of the drug is also comparatively lower. So, depending on the severity of your pain and health needs, you can choose the right medication dose. 



  1. “Carisoprodol”, Wikipedia

  2. carisoprodol (Rx)”, Medscape

  3. “Drug Interactions between ibuprofen and Soma”, Drugs

  4. Carisoprodol Withdrawal After Internet Purchase”, journals.lww