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Nootropics For ADHD- Nootropic Stack For Focus And Attention

Nootropics For ADHD- Nootropic Stack For Focus And Attention


Nootropics help improve the levels of dopamine and Norepinephrine, along with numerous others, which, if present at lower levels, can cause ADHD. They also improve attention span, focus, and memory while reducing hyperactivity, which is primarily associated with ADHD. 



Wondering if Nootropics for ADHD work Or which are the best energy supplements for ADHD? This is where you will find all your answers. 

According to the Forbes website, about 6 million (9.8%) children in the US between the ages of 3 and 17 suffer from ADHD, making it important to focus on this mental health disorder. 

While conventional treatments such as stimulant medication have shown effective results, there is a growing interest in alternative treatments. This blog looks into ADHD and the best prescription Nootropics for ADHD in adults and children. 


Nootropics And ADHD- An Overview 

The term "Nootropic" was first used by Cornelius E. Giurgea in 1972 to describe compounds that primarily activate cognitive functions. The term consists of two Greek words- nöos, meaning thinking, and tropein, which means to guide [1]. 

Also known as "Smart drugs," they are medicinal compounds that improve memory, human thinking, and learning. The FDA (Food and Drug Administration) has approved the medical use of prescription Nootropics to treat several conditions, including ADHD. 

ADHD is a common neurodevelopmental disorder in children that may last into adulthood. 

People with ADHD may experience changes in brain performance associated with a range of behavioral and cognitive issues, including-

  • Inability to concentrate.

  • Disorganization.

  • Mood swings.

  • Daydreaming.

  • Difficulty Multitasking. 

  • Poor planning.

  • Face difficulty getting along with others.



ADHD Statistics At A Glance-

  • Did you know that around 6 in every 10 children in the U.S. suffer from ADHD? 

  • About 35% to 78% of children who are diagnosed with ADHD maintain their symptoms as an adult. 

  • As of 2020, more than 366 million adults worldwide have ADHD [1]. 



How Does Nootropics Help ADHD?

Before we understand how Nootropics help with ADHD, we must know how it is caused. 

A study suggests that unbalanced catecholamine levels are associated with ADHD. Catecholamine is a group of three neurotransmitters, including-

  • Epinephrine- This neurotransmitter helps the brain to think quicker and sharper in stressful events. 

  • Norepinephrine- This chemical plays a key role in managing the sleep cycle, attention, and vigilance. 

  • Dopamine- It helps in driving gratification and motivation. 

 This is mainly because a healthy catecholamine level is essential for the proper functioning of the part of the brain that is associated with ADHD, including attention span, impulse control, and working memory. 

Most prescription Nootropics, similar to the primary prescription medications for ADHD, work by increasing the level of neurotransmitters such as dopamine and norepinephrine in the brain. Elevated levels of these neurotransmitters can help improve the following signs-

  • Improving and managing executive dysfunction. 

  • Enhancing attention span. 

  • Impulsive behavior improvement. 

  • Lowering hyperactivity [2]. 

Along with attention span, Nootropics can also improve memory and motivation in people with ADHD. 




Top 5 Strongest Nootropics For ADHD

Based on clinical studies and scientific research, some effective Nootropics for ADHD management include- 

Methylphenidate for ADHD- 

It is also retailed under the name of Ritalin in the market and is the first-line pharmacological treatment for ADHD in children. It also helps in improving impulsive behavior and hyperactivity in such patients by stimulating the centers in the brain that are often inactive in such patients. 

- Dosage Guidelines

  • Adults may begin with 20 to 30 mg two to three times daily. 

  • Maximum dose- 60 mg. 


Pros of Ritalin for ADHD

Cons of Ritalin for ADHD

It is the first treatment choice for ADHD. 

It can be habit-forming if taken incorrectly. 

Safe for long-term use. 

A few cases of growth retardation in children are noticed. 

It works within 30 to 25 minutes.

It can cause side effects such as headaches, insomnia, stomach pain, and a decrease in appetite. 



Lisdexamfetamine is available under the brand name Vyvanse and is a prescription medication for treating ADHD in children of 6 years and above. 

It helps with ADHD to improve focus and attention span by increasing the secretion of Dopamine and norepinephrine in the brain, which helps regulate vigilance, focus, alertness, and memory. 

- Dosage Guidelines

  • The recommended dose of Vyvanse for children above 6 years and adults is 30 mg once a day. 

  • Maximum dose- 70 mg per day. 


Pros of Vyvanse

Cons of Vyvanse

The effectiveness of Vyvanse lasts for 13 hours. 

It is a Schedule II controlled drug with a risk of abuse.

Chewable tablets are available. 

It takes 1.5 hours to start working. 

Once daily dosage regimen. 

It can affect the growth of the children. 

It can also cause high blood pressure, seizures, hallucinations, sweating, fever, fast heart rate, and confusion.


Modafinil For ADHD

Modafinil is a novel psychostimulant approved for the treatment of Excessive daytime sleepiness, available under the brand name of Modalert or Provigil. 

It is often used off-label to treat ADHD in adults over 18 years. A study published in the Journal of the American Academy of Child and Adolescent Psychiatry suggests that Modafinil is a well-tolerated drug that helps reduce symptoms of ADHD at home and school [3]. It also increases dopamine, Acetylcholine, and Norepinephrine in the brain, thus improving signs of ADHD, as shown in the image below. 




Patients with ADHD are often reported to suffer from a lack of alertness and forgetfulness, which can be enhanced by the secretion of orexin by Modafinil. 



Modafinil for ADHD is not prescribed, so why is it on this list? 

A survey by the National Institutes of Health showcases that about 10 to 30 percent of people do not respond well to ADHD medication. Physicians often advise such patients to get Modafinil 200mg as adjunctive therapy with other ADHD treatment options. 


- Dosage Guidelines

  • Standard Modafinil or Modalert dose is 200 mg. 

  • It should be taken once daily, preferably in the morning. 


Pros of Modafinil

Cons of Modafinil

Works within 30 minutes of intake. 

The health risks associated with Modafinil are nausea, headache, insomnia, hypertension, and nervousness.  

Low risk of abuse. 

The FDA disapproves of using Modafinil for ADHD, but it has been clinically proven to be an effective treatment choice. 

The action lasts 14 hours. 


It is considered the safest Nootropic in the pharmaceutical world by Harvard and Oxford University researchers. 


Modafinil comparison with Ritalin and Vyvanse suggests it is the second treatment option for ADHD. 


Piracetam is a derivative of gamma-aminobutyric acid (GABA) and the first Nootropic in the world. It was first synthesized by Giurgea in UCB Laboratories in Belgium and has been in the market since 1972. 

Piracetam can help improve signs of ADHD by enhancing the secretion of acetylcholine. 

A Clinical Trial by N N Zavadenko suggests that it has a positive therapeutic effect in improving children's attention span and behavioral characteristics. 

- Dosage Guidelines

  • A dosage of 2.4 g of piracetam is advised for adults. 

  • Maximum dose is 4.8 grams daily. 


Pros of Piracetam


The effects of the Nootropic lasts for 8 to 9 hours. 

It takes 1 hour for Piracetam to start working. 


The FDA does not approve the medical use of Piracetam, and it is only available as a supplement. 



Noopept (previously GVS-111) is a Nootropic that T. A. Gudasheva developed at the Zakusov Institute of Pharmacology (Russian Academy of Medical Sciences) [4]. It was developed based on the structure of piracetam and was synthesized in 1996.

In a 2023 article by HealthNews, Noopept is considered to be a reliable cognitive enhancing compound for patients with ADHD [5]. The key benefits of using Noopept for ADHD include the following-

  • Memory Improvement

  • Better creativity

  • Helps in reducing stress and anxiety associated with ADHD. 

  • Enhance concentration and focus. 

- Dosage Guidelines

  • Take 10 to 30 mg of Noopept supplement once a day. 

  • One can take the dosage for up to 56 days at a time.




It takes 20  minutes to start acting and is considered one of the fastest Nootropic in the market. 

The health risks of taking Noopept include Confusion, Seizures, Headache, Anxiety, Brain fog, Irritability, Fatigue, Drowsiness, and Lack of focus. 

It is available in megadose, oral, and sublingual formulations. 

Taking a high amount of Noopept for a long time can result in building tolerance. 


The effect of the Nootropic lasts for 1 to 2 hours. 


Is Using Nootropics For Child ADHD Safe?

Ritalin, Adderall, and Vyvanse are three common Nootropics approved by the FDA for treating ADHD in children. 

Adderall is a prescription stimulant formulated with two compounds- dextroamphetamine and amphetamine. It is considered the first treatment choice for ADHD and is known to reduce impulsive behavior and improve focus and attention in such patients. 

A study by Leslie Briars suggests that 75 to 80 percent of children with ADHD see improvement with Adderall. 

Author’s Note-

Children are more likely to experience side effects as they have a low level of maturity in the body system that involves drug transportation, absorption, elimination, and metabolism. 

We at Healthnaturo advise all parents and caregivers to give special attention before giving any medication to their children. We encourage people to consult a doctor before purchasing any of the Nootropics mentioned above for their kids. 


Supplements And Nootropic Plants For ADHD

Along with the brain stimulants, several supplements and Nootropic plants for ADHD can help manage such symptoms effectively. 

Dopamine Supplements For ADHD

Dopamine is one of the key contributors to ADHD. A study by Nora D. Volkow indicates that dopamine levels are different in people with ADHD and healthy individuals.

A few natural dopamine supplements for ADHD are Probiotics, Curcumin, and Mucuna Pruriens. 

Ashwagandha (Withania Somnifera (L.) Dunal)-

The use of W. Somnifera root extract for 30 days improved cognitive flexibility, reaction time, stress response, executive function, psychomotor speed, and visual memory.

L Tyrosine

L-tyrosine is an amino acid precursor of dopamine and norepinephrine, two key neurotransmitters essential for concentration and focus. 

A Controlled Trial by  Lorenza S Colzato in 2016 suggests that L-tyrosine helps improve task performance in people with ADHD. It is found in many food items, including fish, eggs, seeds, tofu, beans, milk, and meat. 

Ginkgo Biloba For ADHD

Ginkgo is a tree native to China that positively affects a person's cognitive ability, thus improving memory, thinking, and learning. 

Sufei He, University of Traditional Chinese Medicine, indicates that ginkgo can affect the cognitive and behavioral aspects of ADHD. It helps induce attention, willful cognition, and calmness while decreasing irritability.

Bacopa Monnieri-

It is a creeping herb and is considered an adaptogen and a Nootropic.

A study found that taking 225 mg of Bacopa extract for 6 months significantly reduced the symptoms of ADHD, including poor self-control, restlessness, impulsivity, and inattention in 85% of the children. 


It is a brain chemical that occurs in the body naturally and is available as a dietary supplement in the US. 

Using citicoline may improve mood, focus, and attention in users. A study also suggests that choline can help mitigate behavioral deficits and improve memory, hyperactivity, and spatial learning in individuals with ADHD.  


ADHD Nootropics Stack

Nootropic stacking combines multiple Nootropic compounds and supplements to enhance their effects. Stacking helps achieve a synergistic effect (an interaction that results in an effect greater than the sum of their individual effects). 

Modafinil Stacking- 

Modafinil stacking is one of the best nootropic stacks for ADHD and is an effective way to enhance people's attention span. Some compounds considered safe to be staked with Modafinil are Coffee, Nicotine, Choline, and CBD oil. 

Bacopa Monnieri And Rhodiola Rosea

These herbal plants help lower ADHD symptoms such as anxiety and stress. 

Bacopa Monnieri can potentially improve working memory, attention, and overall cognition. 

Caffeine And L-Theanine

L-Theanine is an amino acid that helps promote relaxation by reducing anxiety and stress, which in higher doses can enhance attention span in people. 

Taking coffee with L-theanine supplements helps improve focus and attention in ADHD patients. This combination further helps in reducing the jittery effects associated with caffeine.

Creatine And Acetyl-L-Carnitine

These compounds are very effective and potent in improving cognition and attention span in users. A study by Konstantinos suggests that Creatine supplements also improve short-term memory and intelligence.  


Ritalin, Vyvanse, Adderall, and Modafinil are effective Nootropics for ADHD.

Nootropics help improve the secretion of neurotransmitters such as dopamine, serotonin, and norepinephrine, which, if present at lower levels, can cause ADHD.

Brahmi, also known as Bacopa monnieri, is an ancient herbal remedy that helps in improving inflammation and reducing symptoms of ADHD.

Lion's Mane is a white mushroom known to have numerous medical benefits. So far, no available scientific literature suggests the production or improvement of dopamine, which is one of the primary neurotransmitters involved in ADHD.

No, using Ashwagandha has no positive effect in improving the signs of ADHD.

A 2014 study suggests that Ginkgo biloba is one of the best herbs for ADHD.

Administering Curcumin, Probiotics, Mucuna Pruriens, and exercising can help increase the dopamine level in ADHD patients.

Vitamins B and C are effective in improving ADHD symptoms.


  1. ADHD Statistics In 2023 – Forbes Health.

  2. Nootropics as Cognitive Enhancers- Types, Dosage and Side Effects of Smart Drugs, NCBI. 

  3. A Randomized, Double-Blind, Placebo-Controlled Study of Modafinil Film-Coated Tablets in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder, jaacap. 

  4. Piracetam- An Old Drug With Novel Properties, researchgate. 

  5. Best Nootropics For ADHD in 2023 - HealthNews.