Get 2% OFF at the First BUY (Selected Pills) - Shop Now!

Do muscle relaxers make you sleepy?

Do muscle relaxers make you sleepy?

“Do muscle relaxers make you sleep?” is probably one of the most sought-after questions due to the high probability of people experiencing dizziness after their administration. A study involving Cyclobenzaprine indicates that 30% of people taking a muscle relaxer experience drowsiness [1]. 

Muscle relaxers are ideal for short-term acute pain and are proven to work more efficiently in conjunction with rest and physical therapy. The most commonly prescribed muscle relaxers, such as the Soma pill, Flexeril, and Metaxalone, are identified by the FDA for inducing sleepiness in the user. However, the question here is, how long do muscle relaxers make you drowsy? Or do muscle relaxers make you tired the next day? 

This all-inclusive guide on muscle relaxers will help you understand the “if” and “how” of muscle relaxers, making you sleepy. 


Do muscle relaxers make you sleepy?

If put in one word, the answer to the question would be “YES.” 

Scientific evidence and FDA lists sleepiness, dizziness, and drowsiness as the more predominant adverse sign of muscle relaxers. However, not all muscle relaxers react similarly and induce the exact effect. So we take a deep insight into the association of cyclobenzaprine and Carisoprodol with sleep.  

Does cyclobenzaprine make you sleepy?

Cyclobenzaprine, originally developed to treat muscle spasms, is known to improve sleep in patients with chronic pain disorders such as fibromyalgia [2]. The medical news today reports that dizziness and drowsiness are Cyclobenzaprine's two common side effects [3]. 

Other trustable sources such as GoodRx further establish if muscle relaxers make you sleepy. It states that the use of Cyclobenzaprine can make you feel sleepy and can make affect your focus and concentration [4].  

Does Soma make you sleepy?




Carisoprodol, the generic version of the Soma pill, is a noncontrolled skeletal muscle relaxant whose active metabolite is Meprobamate. However, unlike Cyclobenzaprine, Carisoprodol has mixed evidence and anecdotes on its correlation with sleepiness. 

Patients under Carisoprodol treatment are at risk of experiencing meprobamate dependency. The withdrawal and toxicity that are associated with Meprobamate are high. 

Sudden discontinuation of the Soma pill can cause withdrawal symptoms, including insomnia (a sleep disorder that can make it hard to fall asleep) [5]. The Rxlist also asserts the inability to sleep as a common side effect of the Soma pill.

 On the contrary, there are pieces of evidence indicating Soma causes sleepiness in users. The website drugs advise users not to operate heavy machinery or drive a vehicle if Carisoprodol makes them sleepy [6]. 

To prevent experiencing sleep issues from Carisoprodol, beginners are advised to buy Soma 350mg over higher doses as they are less prone to causing side effects. 

How long Will You Feel Sleepy?

The sleepiness associated with muscle relaxers lasts as long as their action last in the user. Muscle relaxers can make you sleepy for 4 to 6 hours from the last dose. 

Why do muscle relaxers make you sleepy?




Scientific data and clinical trials have established if muscle relaxers make you sleepy. But it is equally significant to know why muscle relaxers make you sleepy.

To understand why and how muscle relaxants make you sleepy, it is crucial to have a brief insight into their working mechanism.

The mechanism of action of the Soma pill involves its primary metabolite (meprobamate) working at the GABA receptor. Since muscle relaxants are total body relaxers, they help induce sleepiness or grogginess. It also produces a sedative effect that is ideal for evening use [7]. 

Muscle relaxers can also cause drowsiness. This can be very effective for the recovery of people after surgery and injury. It is also an effective option for cases where pain disrupts the normal sleep cycle of a person. The drowsiness imparted by the muscle relaxer involves tamping down the central nervous system. They act on the nerves that aid in stimulating muscle tension [8]. 

Do muscle relaxers make you tired the next day?

There is no direct evidence of muscle relaxers making you tired the next day. Fatigue is not among the notable side effects of muscle relaxers. 

Muscle tiredness occurs when the muscle does not have enough strength. It may result in your muscle being unable to contract or move easily. Chronic medical conditions resulting in wear and tear of muscle may also result in fatigue. 

Since muscle relaxers such as the Soma pill typically work on the central nervous system instead of the muscle fibers, it does not help with tiredness. It makes it common for you to feel tired while administering them. 

Do muscle relaxers make you drowsy when taken with alcohol?

Drinking alcohol with muscle relaxers can be dangerous. Such interactions intensify the sedative effect of the muscle relaxer, which in severe cases may be even fetal. 

The administration of alcohol with muscle relaxers can depress the central nervous system, slowing down brain activity and thus resulting in sleepiness and calmness. When they are taken together, they can have a synergistic effect causing dizziness and drowsiness. 

A study assessing the association between Muscle Relaxers and Drowsiness

Clinical data establishes that muscle relaxers may not always cause drowsiness. In a study sponsored by Cephalon, Inc, patients with acute muscle spasms were treated with extended-release Cyclobenzaprine of 15mg and 30mg. The report's analysis showcases little to no reports of drowsiness [9]. 

Scientific data to demonstrate if muscle relaxers make you sleep

A study by M. D. Robertson states that side effects associated with Carisoprodol therapy include sleepiness, dizziness, and drowsiness [10]. Soma constipation is often reported in a few people, however, it is not a prevalent issue. 


Clinical Studies Experience reported by FDA-

Two double-blind trials on 1387 patients treated with 250mg and 350mg of Soma pill thrice a day for seven days were conducted. The table below displays the adverse effects of Carisoprodol with their frequencies as stated by the FDA [11]. 


Patients with adverse reactions in controlled studies 

Adverse effect


Soma 250mg

Soma 350mg










A clinical trial on skeletal muscle cyclobenzaprine which is known to induce its effect via inhibiting the tonic somatic motor nerve. The study concludes that using the muscle relaxer exhibits a sedative-hypnotic effect and drowsiness [12]. 

Scientific analysis affirms that people with poor metabolic activity may risk developing hypotension and drowsiness from Soma muscle relaxers [13]. 

Side Effects of Muscle Relaxers

The adverse effects of Muscle relaxers are not just limited to making you sleepy. Most of the side effects are mild, and cases of severe effects are not frequent. The other adverse effects of muscle relaxers include:

  • Dry mouth

  • Dizziness

  • Tiredness

  • Drowsiness

  • Sedation

  • Decrease in blood pressure

  • Depression

  • Weakness or fatigue 

All muscle relaxers including Soma affects the heart if not administered properly. Notify your doctor if you experience any of these signs and symptoms. To minimize the risk, it is best to inform your physician of any history of health disorders and abuse. 

Best Time to Take Muscle Relaxers

Most people taking muscle relaxers are often not aware of the best practices while taking the medication. People taking the Soma pill 3 to 4 times a day must take a dose before bed to help them relax and sleep well. 

Some muscle relaxers may cause more sleepiness and drowsiness compared to others. In such cases, it is best to be mindful of the consequences of the medication and be prepared for the possible adverse effects. 

Using muscle relaxers while driving and operating heavy machinery is not advisable. One must also avoid mixing alcohol and other medications, which may elevate dizziness and drowsiness in the user. 

User review on do muscle relaxers make you sleepy

Now that we know the clinical and scientific views on do muscle relaxers make you sleepy let us look at user reviews and anecdotes. It will help you get a better perspective of the effect of muscle relaxers on sleep and fatigue. 







Tips to cope with tiredness related to muscle relaxers




Muscle relaxants are associated with tiredness and are not identified as one of the most prevalent side effects. However, few people indicate muscle relaxers make them tired the next day.

The treatment for recurring tiredness and muscle fatigue depends on their underlying causes and accompanying symptoms. In most cases, muscle tiredness from muscle relaxants improves with rest. However, if you constantly feel groggy and it comes your way of normal working and functioning, it is advisable to consult a physician.

The recommended tips for coping with muscle tiredness and protecting against muscle fatigue and weakness are:

  • Staying hydrated

  • Maintaining a healthy diet 

  • Consult a doctor to develop better treatment strategies

  • Establish a good sleep routine

  • Reduce stress

  • Eliminate the consumption of alcohol 

Do muscle relaxers make you sleep- Our Final Verdict 

One can summarize if a muscle relaxer makes you sleepy by stating its effect on the sleep cycle. In a nutshell, “yes,” muscle relaxants make you sleepy. The generic and the brand version of muscle relaxers are crucial in deciding their impact on sleepiness and drowsiness. Thus, it is ideal for taking muscle relaxer doses at night.

Cyclobenzaprine is distinguished not to affect people's sleep cycle; on the other hand, methocarbamol can make you sleepy.

Unlike most muscle relaxers, the use of Carisoprodol is reported to cause both insomnia and sleepiness in users. 


Using Muscle Relaxers just for Sleep Disorders

Caution: Muscle relaxers are medications that affect skeletal muscle function and decrease muscle tone. The FDA disapproves using muscle relaxers just for sleep disorders. They are prescription pain medications and should be taken accordingly. Using muscle relaxants can help with sleep issues associated with body pain. 



Muscle relaxers help relax the body, which may develop sleepiness and drowsiness in the user. It also induces a sedative effect that makes it unsafe to operate heavy machinery, drive or make crucial judgments while taking muscle relaxers.

The action of muscle relaxers begins within 30 minutes of administration, and the effects typically last for 4 to 6 hours.

Most muscle relaxers make you drowsy. However, the severity may differ in people. Reviews of muscle relaxers and the possibility of drowsiness show that not all people experience drowsiness, and not all muscle relaxers are reported to induce such effects.

Muscle relaxers can produce drowsy and sleepy effects in users. Therefore, taking muscle relaxers at night is advisable. It will assist in inducing a night of good sleep and keeping your pain at bay.

Muscle relaxers act on the central nervous system to induce a calming and relaxing effect on the user.

The use of muscle relaxers just for sleep is not advisable. It is a pain medication, not a prescription drug for sleep disorders. The use of muscle relaxers can be effective with sleep associated with pain.

Yes, the use of Flexeril can cause sleepiness.


  1. The skeletal muscle relaxer cyclobenzaprine is a potent non-competitive histamine H1 receptor antagonist,  The FASEB Journal. 

  2. Pilot Study of Cyclobenzaprine for Treatment of Sleep Disturbance in Aromatase Inhibitor-treated Breast Cancer Patients, clinicaltrials. 

  3. Cyclobenzaprine, oral tablet, medicalnewstoday. 

  4. Cyclobenzaprine (Flexeril), GoodRx.

  5. Soma - Uses, Side Effects, and More, WebMD. 

  6. Carisoprodol: 7 things you should know, drugs. 

  7. Side Effects and Risks of Muscle Relaxers, spine-health.

  8. 10 Drugs That Affect Your Sleep, Healthgrades. 

  9. Muscle Relaxants May Not Always Cause Drowsiness When Effective: A Post-Hoc Analysis of Cyclobenzaprine ER, empr. 

  10. Carisoprodol — Effects on Human Performance and Behavior, researchgate.


  12. The Skeletal Muscle Relaxer Cyclobenzaprine Is a Potent Non-Competitive Antagonist of Histamine H1 Receptors, aspetjournals

  13. Formation of meprobamate from carisoprodol is catalyzed by CYP2C19., Europe PMC.