Tapentadol is a popular opioid medication used to treat acute and chronic pain in people. Its dual mechanism of action makes it a much safer option in the market today, thus leading to a potential rise in its non-prescription users. This opioid analgesic is commonly known as Nucynta and Palexia 100mg, which are FDA-approved for short-term uses. However, it can be taken for an extended period under medical supervision. The incorrect dosing of the analgesic escalates the risk of side effects in the person. Thus, this article is a detailed study of the long-term effects of Tapentadol opioid pain medication and its safety in users.
Tapentadol Effects On The Body
Tapentadol is a centrally-acting analgesic that functions within 30 minutes of intake. This analgesic is a pro-drug that does not depend on the metabolism to exhibit its therapeutic action. Thus making this opioid medicine an alternative treatment for chronic pain when the user does not respond to other medications. Tapentadol further retails under the name Aspadol and Nucynta. It uses a dual antagonist action that makes it less prone to causing side effects in people. Overdosing and improper administration of this opioid medication are vital factors responsible for causing adverse effects.
People who buy Tapentadol online are advised not to take the analgesic for more than three weeks. Non-prescription users of the analgesic can take a break of 21 days before continuing with its intake any further. Using the medication for an extended period profoundly affects the human brain and the CNS system. Thus, it primarily impacts the physical and mental health of the person. You can now get Aspadol tablets at the best price at Healthnaturo, which offers assured discounts and free shipping on all orders.
Long-term Effects of Tapentadol on mental health
Using Tapentadol for an extended period can peak the chances of the users experiencing dependency and addiction. The euphoric effect of Tapentadol is a significant cause of its abuse in people. 
Apart from dependency, the other impacts of Nucynta on the person’s mental health are confusion, sleep disorders, anxiety, restlessness, irritability, etc. [1]. However, studies and Nucynta reviews indicate that prescription Tapentadol is safe and does not show severe side effects and dependency in the user.
Long-term effects of Tapentadol on physical health
|
System |
Effect of Nucynta |
Frequency |
|---|---|---|
|
Gastrointestinal |
Nausea and Vomiting |
Very common (10% or more) |
|
Impaired gastric emptying |
Rare (less than 0.1%) |
|
|
abdominal discomfort, dry mouth |
Common (1 to 10%) |
|
|
Respiratory system |
Cough, respiratory depression, |
Uncommon (0.1% to 1%) |
|
Upper respiratory tract infection |
Common (1 to 10%) |
|
|
Musculoskeletal |
involuntary muscle contractions, muscle spasms |
Common (1% to 10%) |
|
Bone pain |
Uncommon (0.1% to 1%) |
|
|
Ocular system |
Blurry vision |
Common (1% to 10%) |
|
Any form of visual disturbance |
Uncommon (0.1% to 1%) |
|
|
Metabolic activity |
Decrease in appetite |
Common (1% to 10%) |
|
Nervous system |
Dizziness |
Very common (about 24%) |
|
Headache |
Common (about 15%) |
|
|
Sedation, disturbance in attention |
Common (1% to 10%) |
|
|
Memory impairment, confusion, balance disorder |
Uncommon (0.1% to 1%) |
|
|
Coordination issues |
Rare (less than 0.1%) |
Clinical evidence- Safety of persistent use of Nucynta
A study by James E. Wild MD et al. on Tapentadol vs. Oxycodone was done to understand the safety, tolerability, and long-term effects of Tapentadol ER in chronic pain patients [6].
This study indicates that using Tapentadol ER 100mg projected better gastrointestinal tolerability compared to Oxycodone. It helped manage chronic pain in patients for one year with no potential ramifications on the user.
Withdrawal symptoms of Tapentadol
Long-term effects of Tapentadol can cause withdrawal signs in the user. These symptoms are due to the sudden and abrupt discontinuation of opioid medicine. Withdrawals may begin to appear within a few hours of the last dose. Therefore, one must gradually lower the quantity of the analgesic before altogether discontinuing the use of the pain medication. Most physicians incorporate the “opioid tapering” method before the termination of treatment. The typical withdrawal symptoms in users are sweating, anxiety, nausea, upper respiratory issues, insomnia, sweating, etc.
Nucynta Reviews - A testimonial (ratings) on its perdurable uses
The Nucynta reviews help one get a better insight into the effectiveness, ease, and long-term effects of Tapentadol experienced by users. The overall rating of the analgesic on WebMD is 3.3 out of 5, whereas, at drugs.com, it is 6.2 out of 10. However, here is a list of user reviews for long-term analgesic use, highlighting its potency and side effects.
|
Prescription use |
Side effect experienced |
Ratings |
Dosage duration |
Date of review |
Source |
|---|---|---|---|---|---|
|
Body pain |
Mild constipation |
|
5 to 10 years |
15/3/2019 |
WebMD |
|
Chronic neck pain/ migraines |
dizziness, blurred vision, dry mouth, euphoria. Nothing too bad. |
|
1st day |
7/9/2012 |
Askapatient |
|
Fibromyalgia, Dysplasia, and arthritis |
No issues reported |
|
6 years |
21/11/2019 |
Drugs |
|
Body ache pain |
No issues reported |
|
2 to 5 years |
10/10/2015 |
WebMD |
|
Nucynta for fibromyalgia and bursitis |
No issues reported |
|
5 years |
4/6/2010 |
Drugs |
|
DDD with Radiculopathy |
Stomach pain |
|
8 months |
3/4/2013 |
Askapatient |
|
General body pain |
Dry mouth |
|
Less than a month |
11/3/2015 |
WebMD |
|
Scoliosis, fibromyalgia, and RA |
No issues reported |
|
3 years |
6/2/2020 |
Drugs |
